Patent · US Active

Process for the preparation of 3.7-diazabicyclo[3.3.1] nonane compounds

US8148530B2 · kind B2 · utility

2Cited by

0References

3Claims

0Family size

Assignee

Clariant Produkte (Deutschland) GmbH · DE

Inventors

Michael Wessling · Maintal, DE
Barbara Duecker · Mainz, DE
Nicole Nitschke · Eschborn, DE

Key dates

Filing date	Jun 10, 2006
Grant date	Apr 3, 2012
Priority date	—
Expiry date	Sep 10, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D471/08
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to a process for the preparation of 3,7-diazabicyclo[3.3.1]nonane compounds. According to the invention, in a first step, a dicarboxylic acid ester is reacted with a pyridine aldehyde and a primary amine. The piperidone which forms is reacted in a second stage with formaldehyde and a further primary amine. It is essential to the invention that, in the first reaction stage, a C2-C4-alcohol is used as solvent and, in the second reaction stage, a C3-C4-alcohol is used as solvent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.