Patent · US Active

Spiro substituted compounds as angiogenesis inhibitors

US8148532B2 · kind B2 · utility

20Cited by
1References
6Claims
0Family size

Inventor

Key dates

Filing dateFeb 23, 2008
Grant dateApr 3, 2012
Priority date
Expiry dateDec 8, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D239/88
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to compound of Formula I, processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states associated with angiogenesis, such as cancers associated with protein tyrosine kinases, to their use as medicaments for use in the production of inhibition of tyrosine kinases reducing effects in warm-blooded animals such as humans.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.