Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
US8148534B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Apr 25, 2007 |
| Grant date | Apr 3, 2012 |
| Priority date | — |
| Expiry date | Jun 27, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention discloses novel compounds of Formula I: (I) possessing 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, cognitive disorders, and other conditions associated with 11β-HSD type 1 activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.