Tetrahydrocarbazole derivatives as ligands of G-protein coupled receptors

US8148546B2 · kind B2 · utility

Assignee

• Aeterna Zentaris, Inc. · DE

Inventors

• Tilmann Schuster · Großostheim, DE
• Klaus Paulini · Maintal, DE
• Peter Schmidt · Straubing, DE
• Silke Baasner · Schöneck, DE
• Emmanuel Polymeropoulos · Frankfurt, DE
• Eckhard Guenther · Maintal, DE
• Michael Teifel · Weiterstadt, DE

Key dates

• Filing date: Apr 25, 2008
• Grant date: Apr 3, 2012
• Expiry date: Aug 25, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides novel tetrahydrocarbazole compounds according to formula (I) as ligands of G-protein coupled receptors (GPCR) which are useful in the treatment and/or prophylaxis of physiological and/or pathological conditions in mammals mediated by GPCR or of physiological and/or pathological conditions which can be treated by modulation of these receptors.