Immunocompromised rodents as dual color tumor models
US8148600B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Feb 9, 2004 |
| Grant date | Apr 3, 2012 |
| Priority date | — |
| Expiry date | Sep 11, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/0393
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Immunocompromised rodents that have been modified to express a fluorescent protein in substantially all tissues are described. These rodents are useful as models for gene expression, tumor progression and angiogenesis. Also provided are model systems where heterologous tissues fluorescing in a first color are transplanted into hosts that have been modified to fluoresce in substantially all tissues with a second color.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.