Method for characterisation of the quality of sialoglycoproteins via an isoform number I
US8150630B2 · kind B2 · utility
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Key dates
| Filing date | Oct 18, 2006 |
| Grant date | Apr 3, 2012 |
| Priority date | — |
| Expiry date | Mar 10, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6842
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method is described for characterization of the quality of a sialoglycoprotein via its isoform number I which is calculated from the isoform distribution of the capillary electrophoretic analysis of the sialoglycoprotein and represents a quality feature for the batch consistency, storage stability, biological half-life and the biological effectiveness of a therapeutic glycoprotein. Uses of this method are also described.
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