Pharmaceutical formulations for dry powder inhalers comprising a low-dosage strength active ingredient
US8153104B2 · kind B2 · utility
0Cited by
3References
28Claims
0Family size
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Inventors
Key dates
| Filing date | Mar 16, 2005 |
| Grant date | Apr 10, 2012 |
| Priority date | — |
| Expiry date | Nov 21, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/5084
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a formulation to be administered as dry powder for inhalation suitable for efficacious delivery of low-dosage strength active ingredients to the low respiratory tract of patient. In particular, the invention provides a formulation comprising microparticles constituted of microparticles of a low-dosage strength active ingredient and microparticles of an excipient wherein the MMD of the microparticles is comprised between 2 and 15 micron, at least 10% of the microparticles has a mass diameter (MD) higher than 0.5 micron, and the process of preparation thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.