Injectable chitosan mixtures forming hydrogels
US8153612B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 11, 2008 |
| Grant date | Apr 10, 2012 |
| Priority date | — |
| Expiry date | Jun 7, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08J2305/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A chitosan composition which forms a hydrogel at near physiological pH and 37° C., comprising at least one type of chitosan having a degree of acetylation in the range of from about 30% to about 60%, and at least one type of chitosan having a degree of deacetylation of at least about 70% is disclosed. Further disclosed is a chitosan composition which forms a hydrogel at near physiological pH and 37° C., comprising at least one type of chitosan having a degree of deacetylation of at least about 70% and a molecular weight of from 10-4000 kDa, and at least one type of a chitosan having a molecular weight of from 200-20000 Da. Further disclosed are methods of preparation and uses of the chitosan compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.