Synthesis of 4-amino-thalidomide enantiomers
US8153806B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Jul 16, 2010 |
| Grant date | Apr 10, 2012 |
| Priority date | — |
| Expiry date | Jul 16, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides new and useful analogs of 4-amino-thalidomide. These analogs include S(−)-4-amino-thalidomide and R(+)-4-amino-thalidomide. The invention also provides processes for making these analogs. Further, the invention provides methods for inhibiting angiogenesis and treating angiogenesis-associated diseases, including cancer and macular degeneration, by administering these compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.