Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
US8153807B2 · kind B2 · utility
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22Claims
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Assignee
Inventors
Key dates
| Filing date | Apr 23, 2007 |
| Grant date | Apr 10, 2012 |
| Priority date | — |
| Expiry date | Jul 6, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention discloses novel compounds of Formula I: (I) having 11-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11-HSD type 1 activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.