Detecting and handling coincidence in particle analysis
US8154273B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 10, 2008 |
| Grant date | Apr 10, 2012 |
| Priority date | — |
| Expiry date | Aug 5, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2015/1461
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods and systems substantially eliminate data representative of coincident events from particle analyzer data. A fluid sample containing particles for analysis is prepared. Using an electrical or optical measurement device, signals are sensed. Each signal corresponds to events detected in a sub-sample of the fluid sample flowing through a measurement region in the particle analyzer. The existence of coincidence in the events is determined based on measuring a peak and first and second points of each of the signals. The first and second points have a signal value corresponding to a predetermined portion of the peak. Results data based upon the coincident events and non-coincident events is generated. The results data is then analyzed. In various examples, the method is applicable to a variety of particle types, and may be implemented on different types of particle analyzers including hematology analyzer and flow cytometers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.