Cardiac resynchronization therapy optimization using mechanical dyssynchrony and shortening parameters from realtime electrode motion tracking

US8155739B2 · kind B2 · utility

Assignee

• PACESETTER, INC. · US

Inventors

• Allen Keel · San Francisco, US
• Stuart Rosenberg · Santa Clarita, US
• Kyungmoo Ryu · Palmdale, US
• Wenbo Hou · Santa Clarita, US
• Thao Thu Nguyen · Bloomington, US
• Kjell Noren · Solna, SE
• Michael Yang · Thousand Oaks, US

Key dates

• Filing date: Jun 1, 2009
• Grant date: Apr 10, 2012
• Expiry date: Aug 17, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61N1/3684
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Therapy optimization includes tracking electrode motion using an electroanatomic mapping system and generating, based on tracked electrode motion, one or more mechanical dyssynchrony metrics to thereby guide a clinician in therapy optimization (e.g., via optimal electrode sites, optimal therapy parameters, etc.). Such a method may include a vector analysis of electrode motion with respect to factors such as times in cardiac cycle, phases of a cardiac cycle, and therapy conditions, e.g., pacing sites, pacing parameters and pacing or no pacing. Differences in position-with-respect-to-time data for electrodes may also be used to provide measurements of mechanical dyssynchrony.