Process for the coating of biomedical articles

US8158192B2 · kind B2 · utility

Assignee

• Novartis AG · CH

Inventors

• Harald Bothe · Niedernhausen, DE
• Yasuo Matsuzawa · Roswell, US
• Bernhard Seiferling · Goldbach, DE
• Katharina Schmid · Aschaffenburg, DE
• Heike Arndt · Clingen, DE

Key dates

• Filing date: Dec 19, 2007
• Grant date: Apr 17, 2012
• Expiry date: Dec 29, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L27/34
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

The invention relates to a process for the manufacture of a hydrophilic coating on a biomedical article, which comprises treating the biomedical article for a time period of ≦5 minutes with a solution of an organic solvent comprising a polyanionic compound with a number average molecular weight Mn of >5000, wherein the solution comprises less than 10% by weight of water, and wherein the solution is devoid of a cationic polymer.The coated biomedical articles obtainable by the process of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus especially useful in the field of ophthalmic devices.