Patent · US Active

Method for the enantioselective enzymatic reduction of keto compounds using R-specific oxidoreductase

US8158406B2 · kind B2 · utility

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2References
15Claims
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Inventors

Key dates

Filing dateFeb 21, 2006
Grant dateApr 17, 2012
Priority date
Expiry dateApr 20, 2028

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P7/02
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention relates to a process for the enantioselective enzymatic reduction of keto compounds, in particular of 4-halo-3-oxobutyric acid esters, to the corresponding R-alcohols or S-4-halo-3-hydroxybutyric acid esters, respectively, using an R-specific oxidoreductase in the presence of a cofactor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.