Patent · US Active

Gene silencing

US8158414B2 · kind B2 · utility

17Cited by
12References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 23, 2005
Grant dateApr 17, 2012
Priority date
Expiry dateMar 11, 2028

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA23V2002/00
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention relates to unique strategies and constructs for producing a nucleic acid product that down-regulates or prevents expression of a desired target polynucleotide. Such construct may include an expressing cassette having two convergently-oriented promoters each operably linked to a polynucleotide, but not to a terminator. The two polynucleotides are fully identical in sequence over at least 23 nucleotides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.