Chimeric alphavirus replicon particles
US8158418B2 · kind B2 · utility
14Cited by
8References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 17, 2009 |
| Grant date | Apr 17, 2012 |
| Priority date | — |
| Expiry date | Feb 17, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2810/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Chimeric alphaviruses and alphavirus replicon particles are provided, including methods of making and using same. Specifically, alphavirus particles are provided having nucleic acid molecules derived from one or more alphaviruses and structural proteins (capsid and/or envelope) from at least two or more alphaviruses. Methods of making, using, and therapeutic preparations containing the chimeric alphavirus particle, are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.