Chimeric adenoviruses for use in cancer treatment
US8158599B2 · kind B2 · utility
5Cited by
3References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 30, 2009 |
| Grant date | Apr 17, 2012 |
| Priority date | — |
| Expiry date | Aug 12, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/10344
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.