2-indolinone derivatives as multi-target protein kinase inhibitors and histone deacetylase inhibitors
US8158656B2 · kind B2 · utility
0Cited by
11References
12Claims
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Key dates
| Filing date | May 8, 2009 |
| Grant date | Apr 17, 2012 |
| Priority date | — |
| Expiry date | Dec 17, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to 2-indolinone derivatives which are capable of inhibiting protein kinases and histone deacetylases. The compounds of this invention are therefore useful in treating diseases associated with abnormal protein kinase activities or abnormal histone deacetylase activities. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds, and methods of preparing these compounds are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.