Indole and indoline cyclopropyl amide derivatives as EP4 receptor antagonists
US8158671B2 · kind B2 · utility
11Cited by
1References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 22, 2008 |
| Grant date | Apr 17, 2012 |
| Priority date | — |
| Expiry date | Jun 24, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention is directed to indole and indoline cyclopropyl amide derivatives as EP4 receptor antagonists useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis and cancer. Pharmaceutical compositions and methods of use are also included.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.