Method for ameliorating pain by modification of NMDA receptors through inhibition of Src
US8158749B2 · kind B2 · utility
3Cited by
9References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 21, 2011 |
| Grant date | Apr 17, 2012 |
| Priority date | — |
| Expiry date | Jun 21, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16122
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method for ameliorating inflammatory and/or neuropathic pain in a subject by modifying the activity of N-methyl-D-aspartate (NMDA) receptors in cells of the subject by inhibition of the interaction of the unique domain of the tyrosine kinase Src enzyme and the NMDA receptor complex.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.