Patent · US Active

Anticalins

US8158753B2 · kind B2 · utility

11Cited by

3References

15Claims

0Family size

Assignee

Pieris AG · DE

Inventors

Arne Skerra · Freising, DE
Gerald Beste · Munich, DE
Frank Schmidt · Zorneding, DE
Thomas Stibora · Michendorf, DE

Key dates

Filing date	Jan 5, 2010
Grant date	Apr 17, 2012
Priority date	—
Expiry date	Jan 5, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2799/021
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to the production of novel proteins exhibiting bonding activity for certain ligands, the so-called anticalins. To this end, the structure of peptides of the lipocalin family is modified by amino acid replacement in their natural ligand binding pocket using generic engineering methods. Alike immunoglobulin, the anticalin thus obtained can be used to identify or bond molecular structures.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.