Hydroxyalkyl substituted imidazoquinoline compounds and methods
US8158794B2 · kind B2 · utility
17Cited by
164References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 22, 2006 |
| Grant date | Apr 17, 2012 |
| Priority date | — |
| Expiry date | Aug 22, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Certain imidazoquinolines with a hydroxymethyl or hydroxyethyl substituent at the 2-position, and an aryl or heteroaryl substituent at the 7-position, pharmaceutical compositions containing the compounds, intermediates, methods of making and methods of use of these compounds as immunomodulators, for preferentially inducing IFN-α biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.