Patent · US Active

Process for the preparation of Rho-kinase inhibitor compounds

US8158796B2 · kind B2 · utility

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0References
13Claims
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Assignee

Inventors

Key dates

Filing dateMay 21, 2009
Grant dateApr 17, 2012
Priority date
Expiry dateMar 18, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C69/78
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to practical high-yielding synthetic processes to prepare compounds of general Formula III, IV, V, VII, VIII, IX, X, XII, XIV, and XV. Such compounds are useful as final products or can be used as intermediates and be further modified to prepare other desired products such as rho-kinase inhibitors. The present invention is also directed to certain novel compounds and/or novel solid forms of certain compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.