Purine derivatives having, in particular, anti-proliferative properties, and their biological uses

US8163762B2 · kind B2 · utility

Assignees

• CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE · FR
• Institute of Experimental Botany, Academy of Sciences of the Czeck Republic · CZ

Inventors

• Laurent Meijer · Morlaix, FR
• Emile Bisagni · Orsay, FR
• Michel Legraverend · Antony, FR
• Miroslav Strnad · Olomouc, CZ

Key dates

• Filing date: Dec 23, 2009
• Grant date: Apr 24, 2012
• Expiry date: Dec 23, 2029

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention provides 2-, 6, and 9-substituted purine derivatives, particularly 2(1-R hydroxymethylpropylamino)-6-benzylamino-9-isopropyl purine, having, in particular, antiproliferative properties, and suitable for use as pharmaceutical compositions and herbicidal compositions. Also provided are pharmaceutical compositions and herbicidal compositions comprising the 2-, 6, and 9-substituted purine derivatives, and methods of treatment using the 2-, 6, and 9-substituted purine derivatives.