Amide-substituted 8-N-benzimidazoles, method for the production thereof, and use of the same as medicaments

US8163774B2 · kind B2 · utility

Assignee

• Sanofi-Aventis · FR

Inventors

• Elisabeth Defossa · Idstein, DE
• Karl Schoenafinger · Alzenau, DE
• Gerhard Jaehne · Frankfurt, DE
• Christian Buning · Frankfurt am Main, DE
• Georg Tschank · Frankfurt am Main, DE
• Ulrich Werner · Frankfurt am Main, DE

Key dates

• Filing date: Sep 13, 2007
• Grant date: Apr 24, 2012
• Expiry date: Aug 16, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention comprises the use of amino-substituted 8-N-benzimidazoles compounds of formula Iwherein R3, R4-R5, R11 and R20-R21 are hereinafter defined which display a therapeutically utilizable blood sugar-lowering action. These compounds are intended to be particularly suitable in the treatment of diabetes.