Low-molecular inhibitors of cytohesin-family guanine nucleotide exchange factors

US8163788B2 · kind B2 · utility

Assignee

• Rheinische Friedrich-Wilhems-Universitaet Bonn · DE

Inventors

• Michael Famulok · Bonn, DE
• Waldemar Kolanus · Watertown, US
• Markus Hafner · New York, US
• Imke Grune · Koblenz, DE
• Barbara Tappertzhofen · Cologne, DE
• Mirko Theis · Bonn, DE

Key dates

• Filing date: Nov 18, 2005
• Grant date: Apr 24, 2012
• Expiry date: Nov 12, 2028

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2500/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a pharmaceutical composition and the use thereof, wherein the pharmaceutical composition contains compounds selected from a group of general formulas (5), (6), (7) and (8) and/or enantiomers, diastereomers or the pharmaceutically acceptable salts thereof. The pharmaceutical composition is used for treating autoimmune and tumoral diseases and/or for immunosuppresion.