PKC-activating compounds for the treatment of neurodegenerative diseases
US8163800B2 · kind B2 · utility
4Cited by
0References
15Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 28, 2009 |
| Grant date | Apr 24, 2012 |
| Priority date | — |
| Expiry date | Feb 15, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y207/11013
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methods of activate an isoform of protein kinase C (PKC) for the treatment of neurological diseases including Alzheimer's disease and stroke using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids. The present invention also relates to methods of reducing neurodegeneration using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.