Bioinformatically detectable group of novel regulatory genes and uses thereof
US8163896B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Nov 24, 2003 |
| Grant date | Apr 24, 2012 |
| Priority date | — |
| Expiry date | Nov 14, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/4702
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a first group of novel genes, here identified as genomic address messenger or GAM genes, and a second group of novel operon-like genes, here identified as genomic record or GR genes. GAM genes selectively inhibit translation of known ‘target’ genes, many of which are known to be involved in various diseases. Nucleic acid molecules are provided respectively encoding 200 GAM genes, and 1096 GR genes, as are vectors and probes both comprising the nucleic acid molecules, and methods and systems for detecting GAM and GR genes and specific functions and utilities thereof, for detecting expression of GAM and GR genes, and for selectively enhancing and selectively inhibiting translation of the respective target genes thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.