Coated filament for evaporation/condensation aerosol generation of therapeutic agents and methods for using
US8165460B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 26, 2005 |
| Grant date | Apr 24, 2012 |
| Priority date | — |
| Expiry date | Jun 18, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M11/042
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An apparatus for generating an aerosol of a therapeutic agent and methods of using the same are disclosed. The apparatus comprises a heating element having a surface and a composition coating at least a portion of the heating element surface. The composition comprises a carrier and a therapeutic agent, wherein when the heating element surface is heated to at least the vaporization point of the carrier, the carrier vaporizes and releases the therapeutic agent from the composition as an aerosol. The heating element can be a coiled filament. The therapeutic agent can be a small molecule, a polynucleotide, a polypeptide, or a recombinant virus. The apparatus can be incorporated into a delivery device, such as a metered dose inhaler or an exposure chamber.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.