Patent · US Active

Antibiotic clarithromycin micropellet compositions

US8168228B2 · kind B2 · utility

0Cited by

12References

36Claims

0Family size

Assignee

Sandoz AG · CH

Inventors

Indranil Nandi · Yardley, US
Mintong Guo · Plainsboro, US
Chad Gassert · Hoboken, US
Franz Schwarz · Feldbach, AT
Irina Kosilek · Kufstein, AT

Key dates

Filing date	Jan 30, 2004
Grant date	May 1, 2012
Priority date	—
Expiry date	Jul 26, 2028

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K9/1694
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

An oral suspension comprising (a) an antibiotic composition which comprises coated micropellets and optionally one or more excipients, (b) additional excipients, and (c) a solvent, wherein said coated micropellets comprise (i) a core comprising at least one antibiotic; (ii) an inner coating comprising at least one cellulose polymer which is not an enteric coating polymer; and (iii) an outer coating comprising at least one enteric coating polymer, wherein said coated micropellets have a mean particle size of about 100 μm to about 650 μm. The oral suspension of the invention is characterized by a lack of bitter taste.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.