Agonists of bitter taste receptors and uses thereof

US8168403B2 · kind B2 · utility

Assignee

• Deutsches Institut fur Ernahrungsforschung Potsdam-Rehbrucke Stiftung Des Offentlichen Rechts · DE

Inventors

• Bernd Bufe · Ferch, DE
• Wolfgang Meyerhof · Norderstedt, DE
• Christina Kuhn · Michendorf, DE

Key dates

• Filing date: Sep 27, 2010
• Grant date: May 1, 2012
• Expiry date: Sep 27, 2030

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2500/04
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention relates to agonists of the human bitter-taste receptor hTAS2R40 and their role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block hTAS2R40 bitter taste transduction or bitter taste response.