Polymeric sulfated surfactants for capillary electrophoresis (CE) and CE-mass spectrometry (CE-MS)
US8168440B2 · kind B2 · utility
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4References
7Claims
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Key dates
| Filing date | Mar 28, 2007 |
| Grant date | May 1, 2012 |
| Priority date | — |
| Expiry date | Jan 4, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/255
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present invention relates generally to methods for enantiomeric separation of complex chemical mixtures using micelles of surfactant molecules that have a sulfate or sulfonate head group, a chiral selector, a linker, and a hydrophobic tail. Also provided are micelle compositions with sulfate or sulfonated head groups, methods of manufacture, and applications thereof. In particular, the micelles of the present invention provide an efficient enantiomeric separation and detection techniques for use in capillary electrophoresis and capillary electrophoresis with mass spectrometry.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.