Use of consensus sequence as vaccine antigen to enhance recognition of virulent viral variants
US8168771B2 · kind B2 · utility
2Cited by
1References
2Claims
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Assignee
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Key dates
| Filing date | Jan 31, 2006 |
| Grant date | May 1, 2012 |
| Priority date | — |
| Expiry date | Apr 17, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/24234
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides consensus sequences for hepatitis C virus 1a and 1b. Also provided are non-synonymous changes for each residue of the consensus sequences. These sequences are useful as compositions or vaccines for prophylactic use or treating HCV-infected individuals. Also provided are methods for lessening the chances for a HCV-infected individual to enter a chronic phase of infection and methods of diagnosing an individual with HCV 1a or HCV 1b infection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.