Patent · US Active

Substituted piperazinyl-pyrrolidine compounds useful as chemokine receptor antagonists

US8168788B2 · kind B2 · utility

6Cited by
15References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 17, 2010
Grant dateMay 1, 2012
Priority date
Expiry dateDec 17, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D473/32
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to compounds useful as Chemokine Receptor antagonists. Compounds of general formula I are provided:or pharmaceutically acceptable salts thereof. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions for the inhibition of Chemokine Receptors and also for the treatment of various diseases, conditions, or disorders, including acute or chronic inflammatory disease, cancer or osteolytic bone disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.