Methods and compositions involving miRNA and miRNA inhibitor molecules

US8173611B2 · kind B2 · utility

Assignee

• ASURAGEN, INC. · US

Inventors

• David Brown · Brighton, US
• Lance Ford · Austin, US
• Angie Cheng · Austin, US
• Rich Jarvis · Austin, US
• Mike Byrom · Austin, US
• Dmitriy Ovcharenko · Austin, US
• Eric Devroe · Pflugerville, US
• Kevin Kelnar · Kyle, US

Key dates

• Filing date: Nov 14, 2005
• Grant date: May 8, 2012
• Expiry date: Dec 4, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/178
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention concerns methods and compositions for introducing miRNA activity or function into cells using synthetic nucleic acid molecules. Moreover, the present invention concerns methods and compositions for identifying miRNAs with specific cellular functions that are relevant to therapeutic, diagnostic, and prognostic applications wherein synthetic miRNAs and/or miRNA inhibitors are used in library screening assays.