Compounds which modulate the CB2 receptor

US8173638B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Angela Berry · Gaylordsville, US
• Pier Francesco Cirillo · Woodbury, US
• Eugene Richard Hickey · Danbury, US
• Doris Riether · Biberach an der Riß, DE
• David Thomson · Ridgefield, US
• Lifen Wu · New Milford, US

Key dates

• Filing date: Nov 15, 2007
• Grant date: May 8, 2012
• Expiry date: Aug 6, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.