Biofilm-inhibiting effect and anti-infective activity of N,C-linked aryl isoquinolines and the use thereof

US8173673B2 · kind B2 · utility

Assignee

• Julius-Maximilians-Universitat Wurzburg · DE

Inventors

• Gerhard Bringmann · Würzburg, DE
• Tanja Gulder · San Diego, US
• Ute Hentschel · Coburg, DE
• Frank Meyer · Mannheim, DE
• Heidrun Moll · Coburg, DE
• Joachim Morschhäuser · Veitshöchheim, DE
• Alicia Ponte-Sucre De Vanegas · Coburg, DE
• Wilma Ziebuhr · Ismaning, DE
• August Stich · Gerbrunn, DE
• Reto Brun · Therwil, CH
• Werner E.G. Müller · Cologne, DE
• Virima Mudogo · Kinshasa, CD

Key dates

• Filing date: Sep 27, 2007
• Grant date: May 8, 2012
• Expiry date: Apr 16, 2028

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Anti-infective and biofilm-inhibiting activities of aryl isoquinoline-derivatives of the general formulae 1 to 3are described.