Patent · US Active

Recombinant Factor X with no glycosylation and method for preparing the same

US8173777B2 · kind B2 · utility

1Cited by

1References

18Claims

0Family size

Assignee

Juridical Foundation the Chemo-Sero-Therapeutic Research Institute · JP

Inventors

Kenji Soejima · Kikuchi, JP
Takayuki Imamura · Hamamatsu, JP
Ryoichi Kawamura · Kikuchi, JP
Hiroshi Nakatake · Kikuchi, JP
Arisa Maeyashiki · Kikuchi, JP
Hitomi Togo · Kikuchi, JP

Key dates

Filing date	Oct 8, 2008
Grant date	May 8, 2012
Priority date	—
Expiry date	Oct 8, 2028

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.