Compositions and methods for identifying transforming and tumor suppressor genes
US8178317B2 · kind B2 · utility
4Cited by
2References
35Claims
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Key dates
| Filing date | May 1, 2008 |
| Grant date | May 15, 2012 |
| Priority date | — |
| Expiry date | Dec 20, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/178
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are nucleic acids, proteins, vectors, cells, kits, devices and methods useful for identifying regulatable proteins that are able to complement components of cellular signaling pathways. Also provided are compositions and methods using these complementing genes directly as markers for cancer diagnosis or prognosis and as targets for anti-neoplastic therapeutics. Further provided are methods for using changes caused by expression of the complementing genes to indirectly identify associated genes to be used as markers for cancer diagnosis or prognosis and as targets for anti-neoplastic therapeutics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.