cMET inhibitors

US8178534B2 · kind B2 · utility

Assignee

• Takeda Pharmaceutical Company Limited · JP

Inventors

• Jerome C. Bressi · San Diego, US
• Shaosong Chu · 浮桥镇, CN
• Philip Erickson · San Diego, US
• Mallareddy Komandla · San Diego, US
• Lily Kwok · San Diego, US
• John David Lawson · San Diego, US
• Jeffrey Alan Stafford · San Diego, US
• Michael B. Wallace · San Diego, US
• Zhiyuan Zhang · Beijing, CN
• Sanjib Das · Narayanpur, IN

Key dates

• Filing date: Aug 14, 2009
• Grant date: May 15, 2012
• Expiry date: Apr 23, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the following formula are provided for use with cMET:wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using the compounds.