Tricyclic derivatives as potent and selective histone deacetylase inhibitors
US8178577B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | May 8, 2009 |
| Grant date | May 15, 2012 |
| Priority date | — |
| Expiry date | Apr 27, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/32
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to certain tricyclic derivatives which are capable of inhibiting histone deacetylases. The compounds of this invention are therefore useful in treating diseases associated with abnormal histone deacetylase activities. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds, and methods of preparing these compounds are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.