Polypeptide sequence involved in the modulation of the immunosuppressive effect of viral proteins
US8178657B2 · kind B2 · utility
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3Claims
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Key dates
| Filing date | Mar 30, 2005 |
| Grant date | May 15, 2012 |
| Priority date | — |
| Expiry date | Apr 16, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K7/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a polypeptide having a sequence of 7 to 20 amino acid residues, which is capable of modulating the immunosuppressive properties of a viral protein or a fragment thereof, against the host in which it is expressed (immunosuppression-modulatory sequence) when it substitutes the homologous sequence of the viral protein or fragment, the polypeptide including the minimum following consensus amino acid sequence:X1Y9Y10Y11CY12X2 wherein, X1 and X2 are selected to impact on the immunosuppressive properties, and Y9 to Y12 represent variable amino acid residues.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.