Patent · US Active

Molecules of the card-related protein family and uses thereof

US8178661B2 · kind B2 · utility

0Cited by
2References
15Claims
0Family size

Assignee

Inventor

Key dates

Filing dateOct 8, 2008
Grant dateMay 15, 2012
Priority date—
Expiry dateJan 6, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q2600/158
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Novel CARD-9, CARD-10, or CARD-11 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated CARD-9, CARD-10, or CARD-11 proteins, the invention further provides CARD-9, CARD-10, or CARD-11, fusion proteins, antigenic peptides and anti-CARD-9, CARD-10, or CARD-11 antibodies. The invention also provides CARD-9, CARD-10, or CARD-11 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a CARD-9, CARD-10, or CARD-11 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.