Method of producing L-lysine
US8183017B2 · kind B2 · utility
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8References
12Claims
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Key dates
| Filing date | Oct 29, 2010 |
| Grant date | May 22, 2012 |
| Priority date | — |
| Expiry date | Oct 29, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P13/08
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The ability and speed with which a coryneform bacterium can produce L-lysine are improved when the coryneform bacterium contains an aspartokinase in which feedback inhibition by L-lysine and L-threonine is substantially desensitized. This is accomplished by successively enhancing the DNA coding for dihydrodipicolinate reductase, the DNA coding for dihydrodipicolinate synthase, the DNA coding for diaminopimelate decarboxylase, and the DNA coding for diaminopimelate dehydrogenase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.