Methods and means for obtaining modified phenotypes
US8183217B2 · kind B2 · utility
16Cited by
96References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 13, 2005 |
| Grant date | May 22, 2012 |
| Priority date | — |
| Expiry date | Jul 13, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y302/01031
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods and means are provided for reducing the phenotypic expression of a nucleic acid of interest in eukaryotic cells by providing aberrant, preferably unpolyadenylated, target-specific RNA to the nucleus of the host cell. Preferably, the unpolyadenylated, target-specific RNA is provided by transcription of a chimeric gene comprising a promoter and a DNA region encoding the target-specific RNA.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.