Suppression of SCN9A gene expression and/or function for the treatment of pain
US8183221B2 · kind B2 · utility
2Cited by
18References
5Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 5, 2008 |
| Grant date | May 22, 2012 |
| Priority date | — |
| Expiry date | Oct 17, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are methods, sequences and nucleic acid molecules used to treat pain. Specifically, the methods and sequences include locally administering molecules that suppress the expression of amino acid sequences that encode for Nav1.7 channels or that otherwise inhibit the function of Nav1.7 channels. Local suppression of Nav1.7 channel levels and/or function will occur in the peripheral sensory neurons of the dorsal root ganglia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.