Pharmaceutically acceptable propylene glycol solvate of naproxen
US8183290B2 · kind B2 · utility
2Cited by
113References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 20, 2010 |
| Grant date | May 22, 2012 |
| Priority date | — |
| Expiry date | Jul 20, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to pharmaceutical compositions comprising propylene glycol solvates of APIs. In particular a 2:1 complex of naproxen sodium to propylene glycol is disclosed which is a crystalline solid. The complex is prepared by crystallization of a mixture of naproxen sodium and propylene glycol from diethyl ether. It is identifiable by its X-ray powder diffraction pattern described herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.