Patent · US Active

Medium and device for proliferation of stem cells and treatment of cancer-related stem cell with resveratrol

US8183297B2 · kind B2 · utility

0Cited by

2References

5Claims

0Family size

Assignee

TAIPEI VETERANS GENERAL HOSPITAL · TW

Inventors

Shih-Hwa Chiou · Taipei, TW
Tsung-Yun Liu · Taipei, TW
Tung-Hu Tsai · Taipei, TW
Jeng-Fan Lo · Taipei, TW
Yi-Ping Yang · Taipei, TW
Fu-Ting Tsai · Taipei, TW
Yu-Chih Chen · Sha Tin, CN
CHIAN -YEU CHIEN · Taipei, TW

Key dates

Filing date	Jul 10, 2009
Grant date	May 22, 2012
Priority date	—
Expiry date	Dec 3, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2501/999
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a device for selecting stem cells with a serum free medium for amplification of stem cells. The invention also relates to a method of treating or preventing diseases caused by cancer-related stem cells. The invention further provides a method of enhancing radiosensitivity of cancer-related stem cells comprising radiotherapy with resveratrol, and the cancer-related stem cell has stronger drug resistance. The present invention further provides that resveratrol promotes differentiation and inhibits teratoma/tumor formation in induced pluripotent stem cells (iPS) and embryonic stem cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.