Method for predicting interaction between protein and chemical
US8185321B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 31, 2007 |
| Grant date | May 22, 2012 |
| Priority date | — |
| Expiry date | Dec 17, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B20/00
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
The present invention provides a method for configuring a pattern recognizer using versatile, readily available data, comprehensive protein data, and comprehensive chemical data, as well as a method for predicting an unknown interaction of a pair by using the pattern recognizer-configuring method. An interaction such as the coupling between a protein and a chemical is used as an index; at least one of four parameters is vectorized; a vector containing elements of the vector derived from each protein and elements of the vector derived from each chemical paired with the protein is created; and a support vector machine (SVM) is applied to this vector and trained to learn them, where the pattern recognizer is configured so as to discriminate between a class to which the first pair belong and a class to which the second pair belong.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.