Vaccine composition comprising a fibronectin binding protein or a fibronectin binding peptide

US8187585B2 · kind B2 · utility

Assignee

• Isconova AB · SE

Inventors

• Bror Morein · Uppsala, SE
• Karin Lövgren Bengtsson · Uppsala, SE
• Jill Ekstrom · Alunda, SE
• Katarina Ranlund · Uppsala, SE
• Birgitta Fromgren · Uppsala, SE
• Carlos Concha Bascunan · Santiago, CL

Key dates

• Filing date: Jul 20, 2011
• Grant date: May 29, 2012
• Expiry date: Jul 20, 2031

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/975
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a composition comprising at least one fibronectin binding protein, and/or at least one a truncated fibronectin binding protein and/or at least one fibronectin binding peptide, all comprising at least one fibronectin binding domain; and at least one iscom matrix complex and/or liposome and/or at least one lipid and at least one saponin, whereby the at least one lipid and the at least one saponin may be in complex, solution or suspension. Further, it regards use thereof for the preparation of a vaccine against a micro organism that comprises at least one fibronectin binding domain. It also relates to a kit of parts comprising at least two compartments, wherein one compartment comprises at least one truncated fibronectin binding protein and/or a fibronectin binding peptide, that comprises at least one fibronectin binding domain, and another compartment comprises an instruction for use and/or an iscom matrix complex and/or an iscom complex and or a liposome. Further it relates to a method for vaccination of an individual.